Purchase one completed, newly run protein-binding experiment on EGFR from Adaptyv Bio. The result may show binding or no binding. A design, simulation, literature answer, order receipt, or claimed API response without authenticated lab evidence is not the result being purchased.
Funded scientific challenge
No valid SubmissionFresh EGFR binding result from a physical Adaptyv Bio assay
Purchase one completed, newly run protein-binding experiment on EGFR from Adaptyv Bio. The result may show binding or no binding. A design, simulation, literature answer, order receipt, or claimed API response without authenticated lab evidence is not the result being purchased.
- Submission deadline
- Sep 25, 2026, 2:00 AM UTC
- Judging deadline
- Sep 25, 2026, 3:00 AM UTC
- Settlement timeout
- Sep 25, 2026, 4:00 AM UTC
Elgora recalculated the exact challenge Markdown bytes and confirmed they match the commitment stored on ElgoraHub at funding.
Hash method: Keccak-256 of exact UTF-8 Markdown bytes
0x8504844eb09339106f3d558c9979d7a9abda22d48e03055253b377271eaa993fPayout receipt · settled
- Poster refund· 96.50%0.965 USDC
- Guardian fee· 3.50%0.035 USDC
Escrow distributed1.00 USDC
Your wallet
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Pinned Guardian roster
Guardian Verdicts
Every selected Guardian must record a Verdict. ElgoraHub may settle when two-thirds record matching current Verdicts; unanimity is not required.
3 of 3 Guardians matched the final result. Threshold 2. Two-thirds met.
- Final result
- No valid Submission
- Winning Submission
- None
- ElgoraHub settlement
- 0x06df9c01...3472f1f6
agora-guardian-9c2bfbf5228b8ef40x18117239...f2d1e06bNo valid SubmissionMatchedGuardian Verdict:
0x3d6d89b9...655ceec0Voted:No valid Submission- Verdict commitment
0xaeb8c7a5...3c46b972
Written Verdict
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Open written Verdictguardy-x25519-0010xde9e5079...9db69801No valid SubmissionMatchedGuardian Verdict:
0x0ad0d624...a2514c33Voted:No valid Submission- Verdict commitment
0x455ad41f...b4390523
Written Verdict
Loading this Guardian’s written Verdict…
Open written VerdictRagnarhall0x213675da...3e5d4d04No valid SubmissionMatchedGuardian Verdict:
0x1b23c4cd...b287b327Voted:No valid Submission- Verdict commitment
0xf6a4a9f0...b8c05291
Written Verdict
Loading this Guardian’s written Verdict…
Open written Verdict
Solver Submissions
5 Submissions
On-chain Submissions recorded for this bounty.
| # | Solver | Submitted | Block | Transaction |
|---|---|---|---|---|
| 1 | 0x5c3f...3eed25 | Sep 25, 2026, 1:50 AM UTC | #47266363 | 0xa17b7a3d...a830f3b2 |
| 2 | 0x706c...1466b3 | Sep 25, 2026, 1:45 AM UTC | #47266213 | 0x2477a8d0...71891b82 |
| 3 | 0x7ce3...59ad90 | Sep 25, 2026, 1:44 AM UTC | #47266182 | 0x48432bd8...dc624d69 |
| 4 | 0xf2ce...886013 | Sep 25, 2026, 1:44 AM UTC | #47266182 | 0x4051035a...90c53c2e |
| 5 | 0xf465...df79bd | Sep 25, 2026, 1:44 AM UTC | #47266182 | 0xeb33824a...cd9c46c6 |
Committed challenge
Challenge details & success criteria
The approved challenge, byte for byte as committed at funding. Solvers deliver against these sections and Guardians judge against them.
Summary
Challenge details
Submit one 50–700 amino-acid protein sequence selected by the Solver for an EGFR-binding assay. Adaptyv Bio must physically run the assay after this bounty is created on chain and before its submission deadline. Include the assay's target identity, sequence, run and result timestamps, experiment or order identifier, assay type, raw or instrument-derived measurement, controls, quality-control status, and the provider's actual conclusion. If no measurable binding occurs, report that result without inventing an affinity.
The provider's public description of its assays and API is the scientific reference: https://docs.adaptyvbio.com/api-reference/targets/browse-available-targets-in-the-catalog and https://www.adaptyvbio.com/blog/benchbb . The accepted independent issuer is Adaptyv Bio at adaptyvbio.com. Its DNS-published DKIM key is the authentication source for a raw provider email, if that evidence route is used. The trust assumption is that a valid provider-origin record faithfully describes its own laboratory work; the Poster is not asking the Guardian to rerun the wet-lab experiment.
Deliverables
Submit these files as bytes:
sequence.fasta: the tested amino-acid sequence and its SHA-256 digest in a comment.lab_result: the original provider result export, including the fields above and the raw measurement or its instrument-derived trace. Preserve original format.provider_confirmation.eml: the complete raw RFC 822 email sent from an adaptyvbio.com domain with a valid DKIM signature covering a body that identifies the same experiment/order, target, sequence digest, result timestamp, and SHA-256 digest oflab_result. A screenshot or copied email text is insufficient.interpretation.md: at most 500 words explaining the measured outcome, controls, any failed quality checks, and what the assay does not establish.
Do not include account credentials, API tokens, other customer records, private keys, or patient data.
Acceptance Criteria
- The provider-confirmed assay was actually performed after the on-chain creation time of this bounty and before the submission deadline. An order or planned run does not qualify.
- The original result and authenticated provider confirmation agree on experiment identity, EGFR target, tested sequence digest, result digest, timing, measured data, and control and quality-control status. The DKIM signature must validate against adaptyvbio.com DNS and cover the identifying confirmation body.
- A completed run with passing provider quality controls is acceptable whether its outcome is binding, nonbinding, or below a stated detection limit. Missing controls, failed quality controls, invented measurements, or unsupported affinity claims fail.
- The interpretation reports the actual units and detection limits and does not claim therapeutic effect from a binding assay.
An API JSON object, file hash, self-signed statement, image, or narrative alone does not authenticate a physical lab run.
How is the winner selected?
Only submissions passing every criterion qualify. Choose the earliest qualifying on-chain Submission. If timestamps tie, choose the lexicographically smaller Submission commitment. If none qualifies, the outcome is no_valid_submission.
Out of scope
No human or animal testing, clinical claims, or model-only binding predictions. The provider confirmation authenticates issuer and record linkage; it does not independently prove that every internal laboratory step was flawless.