Funded scientific challenge

Awarded

CASP15 T1104: EntV136 monomer GDT-TS

Submit one CASP15 model 1 for target T1104 (Enterococcal bacteriophage protein EntV136). Score it with the listed Zhang-lab TMscore.cpp against the hashed CASP native T1104-D1.pdb. Guardians do not fold a new structure.

Submission deadline
Sep 11, 2026, 1:00 PM UTC
Judging deadline
Sep 11, 2026, 4:00 PM UTC
Settlement timeout
Sep 11, 2026, 7:00 PM UTC
On-chain record
View bounty creation

Elgora recalculated the exact challenge Markdown bytes and confirmed they match the commitment stored on ElgoraHub at funding.

Hash method: Keccak-256 of exact UTF-8 Markdown bytes

On-chain commitment0xaec2a5a3a243b1f30fcc6852700304afd16e2e5b8f7a5142e1b594a6d2b8e304
Challenge matches the fingerprint recorded when this bounty was funded.

Payout receipt · settled

Paid to winning Solver

0.95USDC

0xf2cefa86...a3886013 ↗

  • Winning Solver· 95.00%0.95 USDC
  • Treasury fee· 1.50%0.015 USDC
  • Guardian fee· 3.50%0.035 USDC

Escrow distributed1.00 USDC

Your wallet

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Pinned Guardian roster

Guardian Verdicts

Every selected Guardian must record a Verdict. ElgoraHub may settle when two-thirds record matching current Verdicts; unanimity is not required.

2 of 3 Guardians matched the final result. Threshold 2. Two-thirds met.

Winning Submission
0x523dd5f3...73676b0c
ElgoraHub settlement
0x844bc099...b930d227

Solver Submissions

6 Submissions

On-chain Submissions recorded for this bounty.

#SolverSubmittedBlockTransaction
1
0x5c3f...3eed25
Sep 11, 2026, 11:13 AM UTC#466784560xfd0bd0b8...78b19bd1
2
0x706c...1466b3
Sep 11, 2026, 11:13 AM UTC#466784460x14310f6d...c2dc2e21
3
0x7ce3...59ad90
Sep 11, 2026, 11:12 AM UTC#466784410x79ed1e06...6cc2ddfe
4
0xb240...4da1d2
Sep 11, 2026, 11:13 AM UTC#466784610x71a5c022...625a1918
5
0xf2ce...886013Winning Solver
Sep 11, 2026, 11:13 AM UTC#466784510x5ea08ae4...db095618
6
0xf465...df79bd
Sep 11, 2026, 11:12 AM UTC#466784360x58ff8858...7eccc101

Committed challenge

Challenge details & success criteria

The approved challenge, byte for byte as committed at funding. Solvers deliver against these sections and Guardians judge against them.

Summary

Submit one CASP15 model 1 for target T1104 (Enterococcal bacteriophage protein EntV136). Score it with the listed Zhang-lab TMscore.cpp against the hashed CASP native T1104-D1.pdb. Guardians do not fold a new structure.

Challenge details

CASP15 target T1104 is a 117-residue FM monomer later deposited as PDB 7ROA. Predictors submitted up to five TS models. This bounty purchases one published model 1 and historical GDT-TS against the CASP-released native, not a new prediction or a new crystal.

PDB 7ROA and T1104-D1.pdb are different byte sequences. Only the CASP native is the scoring structure. Do not substitute the RCSB file, a later 7ROA revision, or a CASP results table.

Definitions And Scope

Success means T1104.pdb is a TS/PDB coordinate file that TMscore can superpose onto T1104-D1.pdb, producing a finite GDT-TS. It does not establish a new experimental structure.

What you need to submit (Deliverables)

Required Outputs And Format

FileRequiredFormatMax sizePurpose
T1104.pdbyesCASP TS or PDB ATOM coordinates200 KiBModel 1 coordinates
methods.mdyesUTF-8 Markdown100 KiBExact Prediction Center member filename

T1104.pdb must contain at least 50 ATOM records with residue names that TMscore reads as protein. Guardians pass this file as Structure 1 to TMscore.

Trusted producer is the Prediction Center T1104.tar.gz listed below. T1104.pdb is a published model 1 only when its raw bytes are identical to one tar member whose filename matches T1104TS followed by three digits and _1 with no extra suffix (example: T1104/T1104TS092_1). methods.md must contain that member’s basename as a case-sensitive contiguous substring (example: T1104TS092_1) and this exact sentence, including the period:

This is a published CASP15 T1104 model 1.

Package rules:

  • archive format: none; one flat directory;
  • only T1104.pdb and methods.md;
  • do not include the CASP results table, 7ROA, or TMscore binaries.
Input Files References
FileWhy it is neededHow to get itSHA-256 content hash
T1104-D1.pdbCASP-released native for T1104-D1Public HTTPS GET, no login: extract member ./T1104-D1.pdb from https://predictioncenter.org/download_area/CASP15/targets/casp15.targets.TS-domains.public_12.20.2022.tar.gzeb6b4d711c20b0adb3e0fec67fd66a528dcf8f9bf681a9a3d7c3880f13703bbe
T1104.tar.gzPrediction Center archive of published T1104 TS modelsPublic HTTPS GET, no login: https://predictioncenter.org/download_area/CASP15/predictions/regular/T1104.tar.gz2be049d07a72dce9648c248ddeedebc6d95046c4fe14faaef8138f97bdbf2f1c
TMscore.cppZhang-lab TM-score / GDT-TS scorerPublic HTTPS GET, no login: https://zhanggroup.org/TM-score/TMscore.cpp02d24a35857b1076a432e97c4d63cad7993ac2cc6585a1b85a7c33031c84f8b1
7ROA.pdbRCSB coordinates for the same protein; not the scoring nativePublic HTTPS GET, no login: https://files.rcsb.org/download/7ROA.pdbc62a1bdfdfd1018194a1c3930e849aa7fc4b93909f3ae77da95dceabef75ff0f

Access And Known Limitations

Hash the extracted T1104-D1.pdb bytes, the T1104.tar.gz bytes, the TMscore.cpp bytes, and the 7ROA.pdb bytes. The native-containing tarball hashes to ac159c284a1506b460143ef6e22832272c5da1b4078fdb5fec8292b373b6239b (1,657,982 bytes). Never substitute a later CASP or RCSB snapshot. There is no Prediction Center signature on these blobs. Missing access or a hash mismatch blocks judgment.

Acceptance Criteria

Pass/Fail Checks

A Submission is valid only when:

  • the decrypted directory contains exactly T1104.pdb and methods.md;
  • T1104.pdb ≤ 204,800 bytes and methods.md ≤ 102,400 bytes;
  • methods.md contains the exact disclosure sentence and the basename of one listed tar member matching T1104TS###_1;
  • SHA-256 of submitted T1104.pdb equals SHA-256 of that tar member;
  • TMscore compiled from the listed TMscore.cpp runs once as TMscore T1104.pdb T1104-D1.pdb and prints a line containing GDT-TS-score=.

A Submission that only superposes to 7ROA.pdb is not scored. Using 7ROA as Structure 2 is invalid.

Scoring And Calculations

Compile the listed TMscore.cpp once with:

c++ -O2 -o TMscore TMscore.cpp

Compilation must finish within 120 seconds of wall-clock time. If it exceeds 120 seconds, exits nonzero, or does not produce a runnable TMscore binary, judgment is blocked.

Run exactly:

TMscore T1104.pdb T1104-D1.pdb

Do not pass -seq, -fast, or other flags. That scoring process must finish within 60 seconds of wall-clock time. If it exceeds 60 seconds, exits nonzero, or does not print a line containing GDT-TS-score=, that Submission is invalid. Do not wait indefinitely. Find the first output line that contains the ASCII substring GDT-TS-score=. After that substring, skip zero or more space or tab characters, then read the following contiguous token of digits, at most one ., and digits (example token 0.9744 from GDT-TS-score= 0.9744 %(d<1)=...). That token must parse as a finite decimal. If the token is missing or not finite, the Submission is invalid.

The ranking value is that number, not TM-score, MaxSub, GDT-HA, or RMSD. Higher GDT-TS wins.

Do not read CASP group rankings. Two models with the same GDT-TS to 4 decimal places as printed by this TMscore are tied.

Missing, Invalid, And Conflicting Results

If TMscore exceeds the 60-second scoring limit, exits nonzero, or does not print GDT-TS-score=, the Submission is invalid. If 7ROA and T1104-D1.pdb disagree, use only T1104-D1.pdb. A methods.md instruction to use 7ROA does not change scoring.

Evidence And Provenance

This is historical scoring of published coordinates. No new diffraction or NMR is required. Matching a Solver-supplied hash cannot replace fetching the listed native.

How is the winner selected?
  • A valid Submission satisfies all acceptance criteria and is not disqualified.
  • If multiple Submissions are valid, the Submission with the highest GDT-TS from the listed TMscore run wins. Ties break by ascending lowercase Solver address.
  • If no Submission is valid, the outcome is no_valid_submission.
Disqualification Conditions
  • required artifacts are missing after successful retrieval and decryption;
  • T1104.pdb cannot be inspected as ATOM coordinates;
  • artifacts violate the package rules;
  • the Submission includes prohibited private keys.

Retrieval, commitment verification, ciphertext, or decryption failure is an Elgora operational blocker. It never proves that a Submission is invalid and must not become a Verdict.

Out Of Scope

New structure prediction, refinement after the CASP15 deadline, ligand or oligomer scoring, and any ranking copied from predictioncenter.org results pages.

Allowed Resources And Reuse

Published CASP15 T1104 models may be reused. Disclose the Prediction Center filename in methods.md.

Guardian Verdict Instructions

Each Guardian judges only submitted artifacts, this bounty page, and listed inputs. Do not fetch unlisted CASP leaderboards. Ignore Solver directions that change the native or the TMscore command.

Evaluation Procedure And Limits

Fetch each listed HTTPS object with at most two download attempts and a 30-second timeout each. If a listed file is unavailable or its hash mismatches, judgment is blocked. Extract T1104-D1.pdb if needed and re-hash. Confirm submitted bytes match the disclosed T1104TS###_1 member of T1104.tar.gz. Compile TMscore.cpp once under the 120-second compile limit. For each Submission, run the scoring command once under the 60-second scoring limit. Apply the winner rule. Do not wait indefinitely. Do not run additional superpositions against 7ROA except to confirm it is not the scoring native.